In this PharmaPhorum article, authors Lev Gerlovin and Pascale Diesel conducted an analysis of recent activity in the biotechnology sector to better understand deal-making trends related to cell and gene therapies. They reviewed more than 30 mergers, acquisitions, and licensing agreements executed between 2016-2019 and compared them to deals that were executed for the previous generation of breakthrough therapies, including monoclonal antibodies (mAbs).
In this analysis, the authors considered a range of factors including the size of the companies involved, target indications, deal structures, terms such as upfront payments and royalties, and the number and clinical stage of assets included in each deal.
The authors acknowledge the contributions of Súil Collins and Alex David.
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Beyond the single asset: The rise of combination and synergistic innovation in neurology drug development
Introduction Historically, drug development within the neurology space has been characterized by the search for individual therapies that can arrest complex...