With many gene therapies in development for an increasing number of indications, their curative promise presents a unique competitive dynamic as they enter the market over the coming years. A one-time treatment with the potential to cure patients could create a “winner takes all” dynamic, whereby second and later entrants for the same indication would have significantly smaller patient populations, such as treatment-resistant or inappropriate patient segments.
Strengthening regulatory systems in low- and middle-income countries: Improving the sustainability of the vaccine innovation ecosystem in Africa
This report explores the challenges in regulating the development, production, safety monitoring and approval of vaccines for use across Africa. The absence of...